Researchers Create One-Dose Ebola Vaccine

Animal tests are promising, but more work needed before human trials.

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2015-04-09

A quick-acting, single-dose Ebola vaccine is safe and effective in nonhuman primates, and may lead to a new human vaccine.

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The experimental vaccine is effective against the West African Makona strain of Ebola Zaire virus, which to date has infected more than 25,000 people -- killing nearly 10,600 -- in the ongoing outbreak in Africa.

The vaccine uses a harmless virus that has a part of the Ebola virus inserted into it. In nonhuman primates, the vaccine triggered an immune response against Ebola, according to the study.

"These findings may pave the way for the identification and manufacture of safer, single-dose, high-efficiency vaccines to combat current and future Ebola outbreaks," expert said.

"We are excited at the possibility of helping develop a way to stop this deadly disease. We have a lot more work to accomplish but it's important to note that this is a big step," expert added.

With a growing population in West Africa, there will be increased contact between people and Ebola virus hosts such as bats, potentially leading to other large outbreaks, the researchers said.

While efforts to develop new vaccines may not be helpful in the current Ebola outbreak, they could prove important in fighting future outbreaks.

In addition, it should be noted that animal research findings do not always translate to humans.

Source: HealthDay News