Science

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Detecting early-stage malarial infection: New prototype device recognizes electrical properties of infected cells as signatures of disease

Researchers at MIT have found a way to detect early-stage malarial infection of blood cells by measuring changes in the infected cells' electrical properties.

The scientists, from the laboratories of MIT's Anantha Chandrakasan and Subra Suresh — who is now president of Carnegie Mellon University — have built an experimental microfluidic device that takes a drop of blood and streams it across an electrode that measures a signal differentiating infected cells from uninfected cells. The work, published Aug. 8 in the journal Lab on a Chip, is a first step toward a field-ready, low-cost, portable malaria-detection device.

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Cosmology in the lab using laser-cooled ions: Taking a look back at the beginning of our universe: QUEST researchers at PTB generate and investigate symmetry breaking in ion Coulomb crystals

Scientists would love to know which forces created our universe some 14 billion years ago. How could - due to a breaking of symmetry - matter, and thus stars and galaxies, be created from an originally symmetrical universe in which the same conditions prevailed everywhere shortly after the Big Bang. Now, the Big Bang is an experiment that cannot be repeated. But the principle of symmetry and its disturbance can definitely be investigated under controlled laboratory conditions. For this purpose, scientists from the Excellence Cluster QUEST* at the Physikalisch-Technische Bundesanstalt (PTB) used laser-cooled ions in so-called "ion Coulomb crystals".

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The picture shows ytterbium ions in an ion Coulomb crystal, taken with an EMCCD camera (electron multiplying CCD camera). The ionized atoms fluoresce in the laser light; the distance between the ions is approx. 10µm to 20 µm. (a) Radial symmetry: At a high radial trap enclosure, the ionized atoms line up like a string of pearls. The radial potential felt by the positively charged particles is depicted at the bottom left. (b) Mirror symmetry: If the strength of the radial enclosure changes, the ions become free to avoid each other, and the crystal adopts a new, energetically more favourable structure. Hereby, two energetically equivalent configurations can be chosen from. Areas which do not communicate with each other decide independently of each other on a new orientation. Topological defects occur where two areas which have made different "decisions" collide. The black-and-white images show fluorescing ytterbium ions.

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Researchers Optically Levitate a Glowing, Nanoscale Diamond

Researchers at the University of Rochester have measured for the first time light emitted by photoluminescence from a nanodiamond levitating in free space.

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The researchers show photoluminescence from an optically levitated nano diamond.

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What lies beneath

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A slice through the southern highlands of Mars

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Raman pixel by pixel

New data processing protocol enables feature-based recognition of Surface-enhanced Raman spectra for intracellular molecule probing of biological targets. It relies on locally detecting the most relevant spectra to retrieve all data independently through indexing.

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Material in dissolvable sutures could treat brain infections, reducing hospital stays

A plastic material already used in absorbable surgical sutures and other medical devices shows promise for continuous administration of antibiotics to patients with brain infections, scientists are reporting in a new study.

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The challenge of delivering to the brain a continuous regimen of antibiotics in case of infection could be met with plastic nanofibers that release medication directly to the affected site.

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Hubble Sees a Bright Light from the Serpent Bearer

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Perseid meteors to light up summer skies

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A Perseid meteor (at left) seen in August 2010 above the four enclosures of the European Southern Observatory’s Very Large Telescope at Paranal, Chile.

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New Study Finds that the Price of Wind Energy in the United States Is Near an All-Time Low

But continued Federal policy uncertainty and low natural gas prices create headwinds for the sector

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The Odd Couple: Two very different gas clouds in the galaxy next door

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