Health

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HIV vaccine elicits antibodies in animals that neutralize dozens of HIV strains

NIH study results represent major advance for structure-based HIV vaccine design.

An experimental vaccine regimen based on the structure of a vulnerable site on HIV elicited antibodies in mice, guinea pigs and monkeys that neutralize dozens of HIV strains from around the world. On June 4, the findings were reported in the journal Nature Medicine by researchers at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and their colleagues.

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World Bank launches Sustainable Development Bond to Focus Attention on Improving the Health and Nutrition of Women, Children and Adolescents

The World Bank (International Bank for Reconstruction and Development, IBRD, Aaa/AAA) has issued a CAD 60 million 10-year Eurobond that raises funds for its sustainable development activities around the world. Japan Post Insurance was the sole investor in this transaction.

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NCI-MATCH precision medicine clinical trial releases new findings, strengthens path forward for targeted cancer therapies

The National Cancer Institute’s Molecular Analysis for Therapy Choice (NCI-MATCH) trial, the largest precision medicine trial of its kind, has achieved a milestone with the release of results from several treatment arms, or sub-studies, of the trial. The new results offer findings of interest for future cancer research that could ultimately play a role in bringing targeted treatments to patients with certain gene abnormalities, regardless of their cancer type.

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Bigger human brain prioritizes thinking hub – at a cost

NIH study finds Information integration trumps emotional, sensory, motor functions.

Some human brains are nearly twice the size of others – but how might that matter? Researchers at the National Institute of Mental Health (NIMH) and their NIH grant-funded colleagues have discovered that these differences in size are related to the brain’s shape and the way it is organized. The bigger the brain, the more its additional area is accounted for by growth in thinking areas of the cortex, or outer mantle – at the expense of relatively slower growth in lower order emotional, sensory, and motor areas.

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Even a shark’s electrical “sixth sense” may be tuned to attack

NIH-funded study illustrates how evolution may shape the senses.

Imagine having superhuman hearing. You’re at a noisy, cocktail party and yet your ears can detect normally inaudible sounds made by your friends’ muscles as they lean in to dish the latest gossip. But, unlike normal hearing, each of these sounds causes your ears to react in the same way.

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June 1: No More Formaldehyde In Wood Products Made, Sold In U.S.

The new rules also limit the amount of formaldehyde emitted from wood products produced domestically or imported from overseas

This Friday is a big day for American consumers — and most don’t even realize it. As of June 1, 2018, it is illegal to manufacture or import composite wood products in the United States if they contain excessive amounts of formaldehyde.

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NIH scientists show how tularemia bacteria trick cells to cause disease

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A female Aedes mosquito.

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Insufficient vitamin D linked to miscarriage among women with prior pregnancy loss

NIH study suggests the importance of preconception vitamin D in maintaining pregnancy.

Among women planning to conceive after a pregnancy loss, those who had sufficient levels of vitamin D were more likely to become pregnant and have a live birth, compared to women with insufficient levels of the vitamin, according to an analysis by researchers at the National Institutes of Health.

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NIH researchers identify how eye loss occurs in blind cavefish

Study yields potential clues to understanding eye disease and blindness in people.

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Photographs of Astyanax mexicanus, surface form with eyes (top) and cave form without eyes (bottom).

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Self-tuning brain implant could help treat patients with Parkinson’s disease

NIH BRAIN Initiative-funded research a key first step to improving deep brain stimulation.

Deep brain stimulation has been used to treat Parkinson’s disease symptoms for 25 years, but limitations have led researchers to look for ways to improve the technique. This study describes the first fully implanted DBS system that uses feedback from the brain itself to fine-tune its signaling. The study was supported by the National Institutes of Health’s Brain Research through Advancing Innovative Technologies (BRAIN) Initiative and the National Institute of Neurological Disorders and Stroke (NINDS).