Health

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Democratic Republic of the Congo begins first-ever multi-drug Ebola trial

The Ministry of Health of the Democratic Republic of the Congo (DRC) on November 26, announced that a randomized control trial has begun to evaluate the effectiveness and safety of drugs used in the treatment of Ebola patients. The trial is the first-ever multi drug trial for an Ebola treatment. It will form part of a multi-outbreak, multi-country study that was agreed to by partners under a World Health Organization (WHO) initiative.

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Clinical trial of investigational Ebola treatments begins in the Democratic Republic of the Congo

An international research team has begun patient enrollment in a clinical trial testing multiple investigational Ebola therapies in the Democratic Republic of the Congo (DRC). The randomized, controlled trial is enrolling patients of any age with confirmed Ebola virus disease (EVD) at a treatment unit in the city of Beni operated by ALIMA (The Alliance for International Medical Action), a medical humanitarian organization.

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WHO and partners launch new country-led response to put stalled malaria control efforts back on track

Reductions in malaria cases have stalled after several years of decline globally, according to the new World malaria report 2018. To get the reduction in malaria deaths and disease back on track, WHO and partners are joining a new country-led response, on November 19, launched, to scale up prevention and treatment, and increased investment, to protect vulnerable people from the deadly disease.

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NIH researchers discover neural code that predicts behavior

Neurons in an ancient part of the brain encode decisions based on visual information.

Scientists at the National Eye Institute (NEI) have found that neurons in the superior colliculus, an ancient midbrain structure found in all vertebrates, are key players in allowing us to detect visual objects and events.

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Eyes of CJD patients show evidence of prions

Finding could help early diagnosis, raise concern for eye exams and transplants.

National Institutes of Health scientists and their colleagues have found evidence of the infectious agent of sporadic Creutzfeldt-Jakob disease (CJD) in the eyes of deceased CJD patients. The finding suggests that the eye may be a source for early CJD diagnosis and raises questions about the safety of routine eye exams and corneal transplants. Sporadic CJD, a fatal neurodegenerative prion disease of humans, is untreatable and difficult to diagnose.

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Study explains behavioral reaction to painful experiences

Exposure to uncomfortable sensations elicits a wide range of appropriate and quick reactions, from reflexive withdrawal to more complex feelings and behaviors. To better understand the body’s innate response to harmful activity, researchers at the National Center for Complementary and Integrative Health (NCCIH), part of the National Institutes of Health, have identified activity in the brain that governs these reactions.

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NIH scientists combine technologies to view the retina in unprecedented detail

Technique enables direct imaging of neural tissue; could lead to earlier detection of diseases affecting eye tissue.

By combining two imaging modalities — adaptive optics and angiography — investigators at the National Eye Institute (NEI) can see live neurons, epithelial cells, and blood vessels deep in the eye’s light-sensing retina. Resolving these tissues and cells in the outermost region of the retina in such unprecedented detail promises to transform the detection and treatment of diseases such as age-related macular degeneration (AMD), a leading cause of blindness among the elderly.

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NIH scientists illuminate causes of hepatitis b virus-associated acute liver failure

National Institutes of Health scientists and their collaborators found that hepatitis B virus (HBV)-associated acute liver failure (ALF) — a rare condition that can turn fatal within days without liver transplantation — results from an uncommon encounter between a highly mutated HBV variant and an unusual immune response in the patient’s liver that is mainly sustained by antibody-producing B cells.

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More than 90% of the world’s children breathe toxic air every day

Every day around 93% of the world’s children under the age of 15 years (1.8 billion children) breathe air that is so polluted it puts their health and development at serious risk. Tragically, many of them die: WHO estimates that in 2016, 600,000 children died from acute lower respiratory infections caused by polluted air.

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Soy formula feeding during infancy associated with severe menstrual pain in adulthood

New research suggests that infant girls fed soy formula are more likely to develop severe menstrual pain as young adults. The finding adds to the growing body of literature that suggests exposure to soy formula during early life may have detrimental effects on the reproductive system.