Health

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Mental health disorders common following mild head injury

NIH-funded study identifies risk factors for neuropsychiatric conditions after concussion.

A new study reveals that approximately 1 in 5 individuals may experience mental health symptoms up to six months after mild traumatic brain injury (mTBI), suggesting the importance of follow-up care for these patients. Scientists also identified factors that may increase the risk of developing post-traumatic stress disorder (PTSD) and/or major depressive disorder following mild mTBI or concussion through analysis of the Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI (link is external)) study cohort. The study was supported by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health. The findings were published in JAMA Psychiatry.

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New Findings Reveal Surprising Role of the Cerebellum in Reward and Social Behaviors

NIH-funded study sheds new light on brain circuits related to affective and social dysfunction.

A new study in rodents has shown that the brain’s cerebellum—known to play a role in motor coordination—also helps control the brain’s reward circuitry. Researchers found a direct neural connection from the cerebellum to the ventral tegmental area (VTA) of the brain, which is an area long known to been involved in reward processing and encoding.

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Guinea Worm Disease Could Soon be Wiped Out, Experts Say

There were just 28 reported human cases of Guinea worm disease (GWD) last year, the U.S.-based Carter Center said Thursday.

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NIH researchers rescue photoreceptors, prevent blindness in animal models of retinal degeneration

Findings set stage for first clinical trial of stem cell-based therapeutic approach for AMD.

Using a novel patient-specific stem cell-based therapy, researchers at the National Eye Institute (NEI) prevented blindness in animal models of geographic atrophy, the advanced "dry" form of age-related macular degeneration (AMD), which is a leading cause of vision loss among people age 65 and older. The protocols established by the animal study, published January 16 in Science Translational Medicine (STM), set the stage for a first-in-human clinical trial testing the therapy in people with geographic atrophy, for which there is currently no treatment.

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Clinical Trial Testing Fecal Microbiota Transplant for Recurrent Diarrheal Disease Begins

A research consortium recently began enrolling patients in a clinical trial examining whether fecal microbiota transplantation (FMT) by enema—putting stool from a healthy donor in the colon of a recipient—is safe and can prevent recurrent Clostridium difficile-associated disease (CDAD), a potentially life-threatening diarrheal illness. Investigators aim to enroll 162 volunteer participants 18 years or older who have had two or more episodes of CDAD within the previous six months.

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“Zero polio transmission and health for all”, WHO Director-General gives new year’s wish to the people of Afghanistan and Pakistan

WHO Director-General Dr Tedros Adhanom Ghebreyesus highlighted WHO’s commitment to the final push to eradicate polio on a 4-day visit to Afghanistan and Pakistan - the only two countries where wild poliovirus cases were reported last year. He also commended the governments of both countries for their efforts to provide universal access to health services.

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Gut microbes from healthy infants block milk allergy development in mice

NIH-funded study links gut microbiome to food allergy.

New research suggests that the gut microbiome may help prevent the development of cow’s milk allergy. Scientists at the University of Chicago found that gut microbes from healthy human infant donors transplanted into mice protected animals exposed to milk from experiencing allergic reactions, while gut microbes transplanted from infants allergic to milk did not. The findings may inform research to develop microbiome-based therapies to prevent or treat food allergy.

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The science is clear: with HIV, undetectable equals untransmittable

NIH officials discuss scientific evidence and principles underlying the U=U concept.

In recent years, an overwhelming body of clinical evidence has firmly established the HIV Undetectable = Untransmittable (U=U) concept as scientifically sound, say officials from the National Institutes of Health.

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WHO Director-General concludes New Year visit to Ebola-affected areas in the Democratic Republic of the Congo

WHO Director-General Dr Tedros Adhanom Ghebreyesus traveled over the New Year to Ebola-affected areas in the Democratic Republic of the Congo (DRC) to review the response at this critical phase. Efforts to end the outbreak are continuing after recent disruptions, but further interruptions could have serious consequences, he warned.

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NIH study implicates hyperactive immune system in aging brain disorders

Results suggest a breakdown in brain cell waste system triggers a destructive immune reaction.

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In a study of flies, NIH scientists showed how the immune system may be a culprit in the damage caused by aging brain disorders.