Current Bird Flu Has Pandemic Potential
Just a few changes are needed for circulating strains to become contagious to humans, study finds.
Flu viruses currently circulating in birds closely resemble the one that caused the 1918 pandemic that killed about 50 million people worldwide, researchers say.
Only a few differences separate proteins in current flu viruses found in birds and proteins in the virus that caused the 1918 Spanish Flu pandemic, the investigators found.
This suggests that a similar deadly virus could emerge in the near future, according to the study.
"Because avian [bird] influenza viruses in nature require only a few changes to adapt to humans and cause a pandemic, it is important to understand the mechanisms involved in adaptation and identify the key mutations so we can be better prepared," expert said.
"Research findings like this help us assess the risk of outbreaks and could contribute to routine surveillance of influenza viruses," expert added.
It would take just a few mutations for one of the current bird flu viruses to become as deadly and infectious as the 1918 virus, according to the researchers.
The findings demonstrate the value of continued surveillance of avian influenza viruses and reinforce the need for improved influenza vaccines and antivirals to prepare for such a scenario.
Source: U.s. Dept. of Health & Human Services
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