Health

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Releasing an immune system brake could help patients with rare but fatal brain infection

Small-scale, NIH-led clinical study offers early hope for developing a treatment.

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MRI of a PML patient showing significant lesions in the brain (white signal).

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NIH researchers make progress toward Epstein-Barr virus vaccine

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A cryo-EM image of the gH/gL/gp45 candidate vaccine construct

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Kids living near major roads at higher risk of developmental delays, NIH study suggests

Young children who live close to a major roadway are twice as likely to score lower on tests of communications skills, compared to those who live farther away from a major roadway, according to an analysis by researchers at the National Institutes of Health and the University of California, Merced. Moreover, children born to women exposed during pregnancy to higher-than-normal levels of traffic-related pollutants — ultra-fine airborne particles and ozone — had a small but significantly higher likelihood of developmental delays during infancy and early childhood.

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Inaugural WHO Partners Forum launches new push for collaboration on global health

To meet the world’s most pressing health challenges, WHO, governments and global health leaders called for improved partnerships and resourcing to support WHO’s mission to deliver care, services and protection for billions of people by 2023.

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Physicians may overprescribe antibiotics to children during telemedicine visits

Children are more likely to be overprescribed antibiotics for colds, sinus infections and sore throats during telemedicine visits than during in-person visits to primary care providers or urgent care facilities, suggests a study.

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Scientists review influenza vaccine research progress and opportunities

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Colorized structure of a prototype for a universal flu vaccine. The nanoparticle is a hybrid of a protein scaffold (blue) and eight influenza hemagglutinin proteins on the surface (yellow).

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CDC Investigation Notice: Multistate Outbreak of E. coli O103 Infections

A CDC investigation notice of a multistate outbreak of E. coli O103 infections. At this time, a source of these infections has not been identified.

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FDA-approved drug effectively treats rare chronic immune disorder

Small NIH clinical trial conducted in partnership with AstraZeneca.

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Activated eosinophils in the peripheral blood of a patient with idiopathic hypereosinophilic syndrome.

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NIH begins first-in-human trial of a universal influenza vaccine candidate

Investigational vaccine designed to provide broad, durable protection from flu.

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A healthy volunteer receives an experimental universal influenza vaccine known as H1ssF_3928 as part of a Phase 1 clinical trial at the NIH Clinical Center in Bethesda, Maryland. Scientists at NIAID’s Vaccine Research Center (VRC) developed the vaccine.

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Scientists explore new roles for RNA

Cells use RNA to communicate; researchers may be able to translate this information into clinical applications.

The biomolecule ribonucleic acid (RNA) is pivotal to cell function. RNA plays various roles in determining how the information in our genes drives cell behavior. One of its roles is to carry information encoded by our genes from the cell nucleus to the rest of the cell where it can be acted on by other cell components. Thanks to a program supported by the National Institutes of Health, researchers have now defined how RNA also participates in transmitting information outside cells, known as extracellular RNA or exRNA. This new role of RNA in cell-to-cell communication has led to new discoveries of potential disease biomarkers and therapeutic targets.