Health

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Ketamine lifts depression via a byproduct of its metabolism

NIH-funded team finds rapid-acting, non-addicting agent in mouse study.

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A team of NIH intramural scientists and grantees traced ketamine’s rapid antidepressant effects to activation of AMPA receptors by a byproduct of its chemical breakdown called (2R,6R)-HNK (above) – a different mechanism than had been previously assumed.

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Cameroon: US$127 Million to Address Urgent Health Needs of Women and Children in Underserved Northern Regions

The World Bank Board of Executive Directors approved on Tuesday a total of US$127 million to increase the use of and improve the quality of health services in Cameroon, with a focus on reproductive, maternal, newborn, child and adolescent health (RMNCAH) and nutrition services. The funding includes a US$100 million International Development Association (IDA) credit, and a US$27 million grant from the Global Financing Facility (GFF) Trust Fund.

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Age-related macular degeneration before and after the era of anti-VEGF drugs

NIH-funded study of Avastin and Lucentis examines their effects at five years.

In a study of nearly 650 people with the eye disease age-related macular degeneration (AMD), half still had vision 20/40 or better, typically good enough to drive or to read standard print, after five years of treatment with anti-VEGF drugs that are injected into the eye. The authors of the study, funded by the National Eye Institute (NEI) at the National Institutes of Health, say those outcomes would have been unimaginable about 10 years ago, prior to the drugs' availability.

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10,000 Poor Liberian Households to Benefit from Cash Transfers

The World Bank Board of Executive Directors has approved a new financing agreement of US$10 million International Development Association (IDA) credit to provide income support to extremely poor and food insecure households in Liberia. This agreement will also establish key building blocks of a basic national safety net delivery system of Liberia.

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NIH statement on World Asthma Day 2016

On World Asthma Day 2016, the National Institutes of Health reaffirms its commitment to support research to improve the lives of all people with asthma. NIH-funded research has advanced our understanding of asthma as a disease as well as the impact asthma has on the lives of those affected. We have made great strides in learning how to treat and prevent asthma, and we are committed to ensuring that scientific discoveries move quickly into clinical practice to provide the best possible care for all people with asthma.

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Elevated bladder cancer risk in New England and arsenic in drinking water from private wells

A new study has found that drinking water from private wells, particularly dug wells established during the first half of the 20th century, may have contributed to the elevated risk of bladder cancer that has been observed in Maine, New Hampshire, and Vermont for over 50 years. Other risk factors for bladder cancer, such as smoking and occupational exposures, did not explain the excess risk in this region.

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NIH creates Atlas of Human Malformation Syndromes in Diverse Populations

Photographic resource will aid diagnosing genomic diseases in patients of non-European ancestry.

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(From left) Adebowale Adeyemo, M.D., Max Muenke, M.D., and Paul Kruszka, M.D., co-created the Atlas of Human Malformation Syndromes in Diverse Populations with collaborators around the world.

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Autism Diagnosed at Younger Ages

Researcher says this is due to change in screening guidelines for 18- and 24-month-olds.

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'Wandering' a Hazard for More Than a Third of Kids With Autism

In study, many were unaware they might be in danger, couldn't distinguish strangers from people they knew.

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More U.S. Kids Have Chronic Health Problems: Study

Low-income children are experiencing the biggest increases, researchers report.

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